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Quantification of the spread of viral expression of Cre across the AP and NTS of the DVC yielded two groups of mice: 1) a DVC Gnas group that had Gs signaling disrupted in both the AP and NTS and 2) an AP Miss group that lacked viral expression in the AP, while containing viral expression in the NTS (Fig

Yet consistent gains in hard outcomeskidney failure, major cardiovascular events, or mortalityhave not been shown

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