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Research has identified several variants with documented relationships to GLP-1 pathway function and metabolic response, including TCF7L2 (incretin sensitivity), MC4R (hypothalamic satiety signaling), FTO (metabolic set point and satiety baseline), LEPR (leptin receptor sensitivity), and ADIPOQ (adiponectin secretion and insulin sensitivity)

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Journal of Clinical Medicine, 8(10), 1645

PROTECTIVE ACTION OF NL-GHK-CU IN THE NERVOUS SYSTEM Among compounds that have protective effects and can reduce oxidative damage are certain neurotrophic factors, such as brain-derived neurotrophic factor (BDNF)