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While some of these benefits come indirectly via weight loss, GLP-1s seem to also directly impact different organs by reducing inflammation or via other biological pathways

The area may look puffier before it looks slimmer

Research focuses on transcription factors governing adipogenesis, activation of lipolytic pathways, and coordination of intracellular metabolic signaling mechanisms

Diabetes Care 41:25602569

The REWIND trial suggested that dulaglutide might be effective for both primary and secondary cardiovascular prevention in individuals with T2DM (254)