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The aforementioned results indicated that in the ovaries, CXCL10 could bind to IL18R1 to activate downstream p-P65 IFN signaling, which subsequently promoted the transformation of macrophages into pro-inflammatory type I macrophages (Fig

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Clifford BL, Sedgeman LR, Williams KJ, Morand P, Cheng A, Jarrett KE, Chan AP, Brearley-Sholto MC, Wahlstrom A, Ashby JW, Barshop W, Wohlschlegel J, Calkin AC, Liu Y, Thorell A, Meikle PJ, Drew BG, Mack JJ, Marschall HU

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Kober M, Pohl K, Efferth T., 2008

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