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Notably, exendin 939 alleviated CAP-induced acute pain, as well as chronic pain induced by complete Freunds adjuvant (CFA) and spared nerve injury (SNI), in mice without causing hyperthermia associated with other TRPV1 inhibitors

Marein ameliorates diabetic nephropathy by inhibiting renal sodium glucose transporter 2 and activating the AMPK signaling pathway in db/db mice and high glucose-treated HK-2 cells

Instead, results pointed to possible effects across multiple forms of mental-health deterioration, including mood symptoms, anxiety symptoms, addiction-related problems, and serious crisis outcomes

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