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Barrier function, tissue integrity, immune signaling, and the gut's broader relationship with systemic physiology are all deeply interconnected - which means the most meaningful research questions tend to involve multiple systems at once

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Most experts believe that migraine aura is caused by a phenomena in the brain called cortical spreading depression (CSD), a slowly progressing wave of excitability followed by long-lasting neuronal inhibition (Bogdanov 2011a)

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From Loading to Maintenance Doses Most treatment plans start with what we call a loading dose