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Diet plays one of the most significant roles in stimulating GLP-1 naturally

two-way ANOVA with Sidaks multiple comparisons test ( g, h, i )

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These may include nausea, decreased appetite (which can help with weight loss), and minor digestive changes

To the extent that hyperglycemia contributes to renal injury and nephropathy, the antihyperglycemic effects of long-term DPP-4 inhibition might be expected to slow the rate of decline of glomerular function, if this benefit can be sustained for prolonged periods of time [83, 84]