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For example, older individuals or those at a higher risk of elevated potassium levels may begin with a lower dose, often around 50 mg or less

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10.1126/sciadv.ade5041 77 TsuriyaD.KobayashiK.TakeshitaK.HonmaT.KasaiM.MashimoY.et al (2025)

My colleagues and I have noted troubling prescribing practices, including widespread use without adequate patient screening or integration with lifestyle modifications, she adds