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Glutathione is also an important storage and transport form of reduced sulfur owing to the thiol-containing Cys residue incorporated into the tripeptide and its biosynthesis is strongly dependent on the sulfur assimilatory pathway including necessary feedback inhibition mechanisms 63

Animals received the following treatments for 12 days: 0.9% saline, 100 ng/kg or 10 g/kg BPC 157

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Some commenters mentioned that this will allow smaller ACOs with less than 5,000 assigned beneficiaries the opportunity to participate in this program and therefore participate in value-based care, enabling ACOs to build their assigned beneficiary population over time without having their participation in the program jeopardized, with a commenter recommending that CMS continue to pursue additional policies and flexibilities that allow smaller ACOs to participate in the Shared Savings Program