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As a result, interventions capable of attenuating or reversing fibrotic remodelling hold significant therapeutic promise in cardiometabolic disease

Effects of pramlintide, an amylin analogue, on gastric emptying in type 1 and 2 diabetes mellitus

This is substantiated by two large, randomized placebo-controlled trials, the Womens Health Initiative study 11 and the Heart and Estrogen/Progestin Replacement study 12 that found a significant reduction in the incidence of diabetes in women assigned to menopausal estrogen therapy, thus providing evidence for the antidiabetic action of estrogen in women

Going beyond 1mg requires either switching to a 3mL syringe or splitting your dose across two injections per week