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Description

Arachidonate 5-lipoxygenase is essential for biosynthesis of specialized pro-resolving mediators and cardiac repair in heart failure

the clinical translation is incomplete

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Its often described as a triple-agonist because it targets multiple hormone pathways involved in appetite and metabolism

Liu Y, Chen W, Cen Y et al (2023) Hepatocyte ferroptosis contributes to anti-tuberculosis drug-induced liver injury: involvement of the HIF-1/SLC7A11/GPX4 axis