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Dysfunction of T and B cells drives anti-nuclear antibody production through the release of oxidized immunogenic nuclear materials from necrotic rather than apoptotic cells (Perl 2013)

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A Phase I clinical trial established the dosing range of 0.01 to 0.03 mg/kg body weight, with significant tanning after five doses (Dorr et al

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This relaxation not only alleviates TMJ-related symptoms and improves jaw function but also reduces the detrimental effects of clenching and grinding on teeth and supporting structures