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doi:10.7860/JCDR/2015/15219.6492

A more concentrated 5 mg/mL option (5 mg in 1.0 mL) gives smaller draws but needs more precise syringe handling

References Deanfield, John et al., Semaglutide and cardiovascular outcomes by baseline and changes in adiposity measurements: a prespecified analysis of the SELECT trial, The Lancet, Published on October 22, 2025, DOI: 10.1016/S0140-6736(25)01375-3 Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity (SELECT), ClinicalTrials.gov ID NCT03574597,

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Second, repeatedly using the same exact spot within any site can cause lipohypertrophy, which meaningfully reduces absorption over time