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Proportion of BrdU+ cells expressing Prox1 was significantly lower in DG-NR1KO mice than in controls ( p = 5.3 10 5 , t (9.687) = 6.834, n = 8 control and 9 DG-NR1KO mice, independent-sample t test, two-tailed

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SLC1A5 has high affinity for glutamine, particularly in an acidic environment 75 , and is thus more effective at transporting glutamine into cancer cells that thrive in acidic environments 76

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