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Once secreted, it is rapidly degraded by an enzyme called dipeptidyl peptidase-4 (DPP-4)

To the extent the data shows that there would be more than a limited impact on the relative weights initially, which we do not believe will be the case, CMS will be able to further consider the impact and appropriate approach to utilizing this market-based data in the MS-DRG relative weight methodology

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And most importantly, we killed the buy and pray model for good

Absorption is slightly slower here than the abdomen due to lower regional blood flow, but semaglutide's week-long activity curve accommodates this delayed onset effortlessly