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3.2 Mechanisms of resistance to membrane-targeting antifungals: polyenes and azoles 3.2.1 Polyene antifungal antibiotics interact with cell membrane sterols Polyene antifungal agentssuch as nystatin, AMB, and natamycinare broad-spectrum drugs commonly used to treat opportunistic fungal infections caused by Candida , Cryptococcus , Aspergillus , and Lentinus species (Tugume et al., 2023

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Diabetes Care 37 , 242251 (2013)

Their differing mechanistic profiles make them valuable tools for comparative studies of peptide-mediated signaling and cellular regulatory processes.

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