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In particular with the CRISPRa approach, the transcriptional activators that are fused to the dCas9 enzyme will increase the length of the construct, such that a combination of sgRNA and dCas9-transcriptional activators will be too large to load onto a single AAV vector

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Phytotherapy Research, 23(3), 367372

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These same circuits drive cravings for alcohol, nicotine and drugs

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Type I cells seem to have glia like function as they express several ion channels (inward rectifying K+ channel [ROMK], glutamate-aspartate transporter [GLAST], ENaC) which are supposed to clear ion currents [222335]

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doi: 10.1172/jci129188 3 IkegamiHBabayaNNosoS

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