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Oral versus intramuscular cobalamin treatment in megaloblastic anemia: a single-center, prospective, randomized, open-label study

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Phase I metabolism for dihexa Phase I metabolism of dihexa, which was determined using pooled male rat liver microsomes, was found to be veiy low with an average intrinsic clearance (Clin t ) of 2.72 7 / 3 4 and an average half-life of 509.4 minutes

Convert vial amount to micrograms (if needed): mg 1,000 = mcg Concentration: total amount (mcg) total liquid (mL) = mcg/mL Math-only example (shows the concentration step) If a vial is labelled 8 mg (8,000 mcg) and you add 2 mL, the concentration is 4,000 mcg/mL