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Lunges : 3 sets of 10-12 reps per leg (use support if needed)

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Intestinal OCT1 transport and GI intolerance with metformin Given the role of OCT1 in potentially altering local concentrations of metformin, our group (Dujic et al) proposed that a reduction in function of OCT1 might alter the risk of GI intolerance in patients treated with metformin [7]

Brain MRI was performed on admission, under general anesthesia, using a 0.4-T MRI system with a permanent magnet (APERTO Lucent, Hitachi, Tokyo, Japan), with the patient in the prone position