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Meanwhile, the expression levels of GPX4 and related antioxidant components were up-regulated after multiple radiation exposures, and thus keratinocytes manifested limited resistance to ferroptosis

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Other aspects of TCA cycle function in brain are completed around postnatal day 15, indicated by maximum oxidative response in rat brain slices to stimuli at this age (Holtzman et al., 1982), and by sensory-evoked increases in brain glucose utilization in vivo by day 10 in barrel cortex (Melzer et al., 1994) and between days 13 to 18 in auditory and visual areas (Nehlig and de Vasconcelos, 1993)