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For example, in the STEP 1 trial , patients taking semaglutide lost an average of 14.9% of their body weight over 68 weeks , compared with just 2.4% in the placebo group (NEJM study)

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Metabolic Partitioning Investigated for its "leaning" effect

The cause of this reduction was not identified, but may be a regulatory mechanism used by the parasite, or may result from reduced vitamin A absorption (32)

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