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To detect GLP-1 secretion from enteroendocrine cell supernatants, we exploit a reporter cell line that expresses the recombinant GLP-1 receptor in combination with the chAMPion reporter system in a CHO background
[PubMed: 20122447] 256
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As in the prior GLP-1 trials reviewed, the GI side effects early that include vomiting, diarrhea, nausea, and constipation, occur in about half of the participants with initial dosing
The promise and peril of GLP-1 agonists: What we do (and don't) know as of August 2024 Yulan Egan Aug 21, 2024 6 min read Across the past two years, GLP-1 agonistsa class of drugs that treat type 2 diabetes (T2D) and obesityhave not only become a major source of industry discourse, but a household name
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