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No oral formulation available or in advanced development

[12] A further complication of severe deficiency is the neurological complex known as subacute combined degeneration of spinal cord

Studies show improved outcomes in models of osteoarthritis and joint damage, likely mediated through growth factor upregulation and anti-inflammatory pathways

For competitive athletes, the World Anti-Doping Agency's "Non-Approved Substances" category (S0) can apply to compounds not approved for human use even where not individually listed