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So they found a bunch of those people, is that what you're saying

Cartilage-specific deletion of mTOR upregulates autophagy and protects mice from osteoarthritis

The 2mg starting dose was well tolerated in the trial, with gastrointestinal effects -- nausea, diarrhea -- most common at higher doses

doi:10.1016/j.fm.2006.07.004 Witschi A, Reddy S, Stofer B, Lauterburg BH (1992) The systemic availability of oral glutathione

Review article: Putting some muscle into sarcopenia-the pathogenesis, assessment and clinical impact of muscle loss in patients with inflammatory bowel disease