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Interestingly, while BPC-157 promotes healing-associated angiogenesis, research also demonstrates it can inhibit tumor-promoting effects of VEGF signaling via the MAPK pathway in melanoma cell lines, suggesting context-dependent modulation of vascular growth that may preferentially support physiological tissue repair over pathological neovascularization

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Impact of pentadecapeptide BPC 157 on muscle healing impaired by systemic corticosteroid application. Medical Science Monitor.

10.1186/s12866-022-02701-z 96 ViazisN.ArgyriouK.KotzampassiK.ChristodoulouD