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Investigation of the interaction between the class I MHC-related Fc receptor and its immunoglobulin G ligand

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Due to its lipophilic nature, Mel easily penetrates cell membranes and acts as a potent antioxidant by scavenging hydroxyl and peroxyl radicals.15 This antioxidant effect is mediated through increased activity of Glutathione Peroxidase (GSH-Px) and Superoxide Dismutase (SOD), prevention of Catalase Reduction (CAT), and inhibition of Nitric Oxide Synthase (NOS)

Elevated 4-HNE causes damage of cell structure and function through the formation of the stable adducts 4-hydroxyalkenals with proteins, phospholipids, and DNA [91, 92]