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Clinical review of the efficacy and safety of oral semaglutide in patients with type 2 diabetes considered for injectable GLP-1 receptor agonist therapy or currently on insulin therapy

GLP-1s and Vegas Theres currently a thread on TripAdvisor titled Enjoying Vegas when your GLP-1 medications kill the thrill. The original poster said his GLP-1 medications have taken away the desire to gamble, drink and smoke

However, varying responses across doses highlight the need for further research

The most important data comes from a substudy of the phase 2, double-blind, placebo-controlled trial published in The Lancet Diabetes and Endocrinology

Conclusions Retatrutide at low, non-weight-loss doses had anti-cancer activity comparable to anti-PD-1 therapy in this mouse model of pancreatic cancer