tirzepatide vs phentermine GLP-1: how the two biggest weight loss medication classes compare phentermine vs. compounded semaglutide for

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Tirzepatide should not be used in people with type 1 diabetes

No evidence suggests long-term harm from continued appropriate use

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This article provides a summary of the weight reduction effectiveness, glycemic control, and safety of semaglutide (up to a 2.4-mg dose) and tirzepatide (up to a 15-mg dose), with a focus on the Semaglutide Treatment Effect in People with Obesity (STEP) 2, SURPASS-1, and SURPASS-2 trials, which involved patients with type 2 diabetes mellitus