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The finding that tirzepatide binds 3-adrenoceptors with high in silico affinity modulating cAMP/cGMP balance and GLUT4 translocation in cardiomyocytes independently of canonical incretin receptor engagement (Aydos et al., 2025) illustrates that the full mechanism of action of an already-approved drug remains incompletely characterized

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white blood cells rid the area of foreign materials and release molecules to coordinate healing