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Your liver metabolizes most antidepressants through cytochrome P450 enzymes, while semaglutide is broken down primarily by neutral endopeptidase and dipeptidyl peptidase-4 in the bloodstream and tissues

They stimulate the release of growth hormones, which are essential for protein synthesis and muscle growth

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These issues frequently overlap with rapid weight loss and are worth assessing properly rather than guessing at

Resistance exercise offers additional benefits beyond muscle preservation, as it: Improves insulin sensitivity, enhancing the glycemic control effects of GLP-1 medications Reduces musculoskeletal pain, anxiety, and depressive symptoms Increases bone density to support long-term health Cardio recommendations for fat loss Although strength training should be your priority, cardiovascular exercise still plays an important role in your GLP-1 weight loss journey