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Notably, in the SELECT trial, individuals with obesity with established ASCVD without T2D were treated with semaglutide 2.4 mg/week and demonstrated a weight loss of over 9% (59)

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It influences: inflammation levels hormone signalling including GLP-1 nutrient absorption immune responses insulin sensitivity When the gut is under chronic stress from ultra-processed foods, excess sugar, medications, repeated dieting and long periods of poor eating structure metabolic regulation begins to suffer