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Gajski et al

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XL413, an inhibitor of CDC7 kinase, effectively induced senescence in liver cancer cells, simultaneously sensitizing them to the senolytic action of the mTOR inhibitor, AZD8055 [136]

The circadian rhythm governs the sleep-wake cycle, sleep neurons control the transition between wakefulness and sleep, and neurochemical regulation involves various nervous systems and chemical substances ( Sleep is fundamental in regulating the hypothalamic-pituitary-adrenal axis, which is involved in growth hormone (GH) release

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