Researchers have looked into this stress-modulating activity across various models, and the idea that DSIP might help restore homeostasis after stressinstead of just suppressing the responseis pretty interesting
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While the end result wont be as sweet (Food Insight notes that allulose is only 70 percent as sweet as table sugar), replacing table sugar with allulose when baking will lower the calories and prevent blood sugar spikes
[4] Lee P et al
However, under pathological conditions such as tumor development, bone marrow transplantation, severe trauma, infection, inflammatory immune responses, and various AIDs, the expression of immunosuppressive factors is significantly upregulated, inhibiting the normal differentiation of myeloid progenitor cells and leading to abnormal expansion and accumulation of MDSCs