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In people with diabetes, GLP-1s reduce blood sugar to improve diabetes management with a lower risk of complications

This unconscious overconsumption of food contributes to excessive weight gain

The gastrointestinal side effects of semaglutide, nausea, vomiting, diarrhea, affect 20-40% of users

This condition is particularly concerning for individuals with diabetes, high blood pressure, or cardiovascular diseases, as they are already at a heightened risk for vascular complications

So cardiologists will need to counsel patients through that and acclimate them to giving these drugs by subcutaneous injection. His colleague Dennis Bruemmer, MD, PhD, Director of Cleveland Clinics Center for Cardiometabolic Health, already has considerable experience using these drugs for diabetes and weight loss