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This aging mechanism is closely related to various common diseases, including atherosclerosis, hypertension, chronic obstructive pulmonary disease, diabetes, and neurodegenerative disorders ( Current senolytic agents are primarily employed in cancer therapies, such as doxorubicin, trametinib, and cell cycle-targeting drugs like palbociclib ( Although studies have shown that FOXO4-DRI can block the binding of P53 to FOXO4, thereby promoting the apoptosis of senescent cells, the effect of FOXO4-DRI is not limited to alleviating the aging of certain organs

Strokes at time of disease diagnosis in a series of 287 patients with biopsy-proven giant cell arteritis

The impact of a nutritional supplement capsule containing L-methylfolate, methylcobalamin and pyridoxal-5-phosphate as a treatment for diabetic neuropathy was explored by Trippe and colleagues

Next, we assessed the association between GSTM3 level and patient prognosis