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From initial gastrointestinal protection studies, the research expanded to include wound healing, musculoskeletal repair, neurological effects, cardiovascular applications, and cytoprotection against various toxins [2]

Samples must be collected within two to four hours post-administration to capture measurable concentrations, and immediate processing (centrifugation, plasma separation, freezing at 80C) is essential to prevent ex vivo degradation

Differential expression analysis was performed to compare macrophages from patients to those from healthy individuals, in addition to comparing macrophages from inflamed and non-inflamed biopsies to healthy individuals

Although effective, these protocols were lengthy, costly, and at times impracticalespecially for patients needing intermittent therapy, as serial desensitization was required for temporary tolerance for each antibiotic course

Recazens, E., Mouisel, E