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Development of multi-receptor agonists Following the success of single-receptor GLP-1R interventions, in vivo models discovered that unimolecular multi-receptor agonists can exploit glucagons biology to achieve substantial weight loss and glucose modulatory improvements at significantly lower dosages, addressing GLP-1Rs gastrointestinal side effects

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Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation