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GLP-1 receptor agonists mimic gut hormones to curb appetite and slow digestion, a mechanism driving the success of therapies from Novo Nordisk (Ozempic for diabetes and Wegovy for weight loss) and Lilly (Mounjaro for diabetes and Zepbound for weight loss)

Change history 19 November 2024 In the version of this article initially published online, earlier, incorrect versions of the Source data files were posted and are now replaced in the online version of the article

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We have decades and decades of information about it, and the safety record of this drug is exquisite. Lets break down some of the surprising superpowers of metformin: 1