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However, with APAP overdose, GSH is exhausted, resulting in NAPQI accumulation and covalent binding to mitochondrial proteins, ultimately aggravating mitochondrial dysfunction, which is the key mechanism of APAP hepatotoxicity [5, 6]

In addition to delaying gastric emptying, GLP-1RAs exert direct effects on the central nervous system to suppress appetite and promote weight loss [9, 11]

Another explanation for the inconclusiveness of human studies is that these studies largely examine the link between the adult body burden of EDCs and the incidence of disease without regard to the timing of the initial exposure

What is known is that placing a child on a restrictive diet carries risks, including malnutrition and delayed growth

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