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McLaughlin C, MacMillan D, McCardle C, Smith WE

Methods 14 , 331332 (2017) Rohou, A

Selenium Selenium is required for glutathione peroxidases (GPx) important antioxidant enzymes in the brain and other tissues

Given the high degree of expression of GPx-2 in the colon and its overlapping activities with GPx-1, deletion of both GPxs is apparently necessary to develop robust inflammatory responses in the colon (111) that may promote neoplastic changes in this model (72)

277 It utilizes an LNP delivery system to efficiently transport siRNA to liver cells, inhibiting the production of both mutant and wild-type TTR proteins