You risk damaging the peptide
Halpern JP, Boyages SC, Maberly GF, et al
For anyone easing in slowly, or skin that reacts to almost everything, an even gentler on-ramp works well: copper peptides nightly for the first four to six weeks, building barrier strength and tolerance, before introducing retinol just one or two nights a week and expanding from there as skin adjusts
Anti-Aging: Look and feel youthful with science-based anti-aging treatment
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