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This underscores the importance of maintaining mitochondrial homeostasis to prevent the progression of neuropathic symptoms

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SGLT2 inhibitors increase urinary glucose and water excretion and can precipitate euglycemic diabetic ketoacidosis, which may present with thirst, nausea, and vomiting even when blood glucose levels are not severely elevated

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Meanwhile, reduced levels of GSH were identified in post-mortem PD brains, suggesting impaired GSH defense in PD [157]

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