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IGF-1 is considered to be the main anabolic mediator of growth hormone

PD involves the progressive degeneration of dopamine-producing neurons in the substantia nigra, resulting in reduced dopamine neurotransmitter in the striatum as shown in Fig

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This test, which evaluates depressive states through the analysis of immobility and struggle times, demonstrated that the control group displayed minimal depressive-like behaviors, as evidenced by the lowest percentage of immobility