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The X-ray crystal structure of Escherichia coli succinic semialdehyde dehydrogenase

DSIP's relatively short in vitro stability due to enzymatic degradation distinguishes it from more stabilized peptide analogs, making it a useful model for studying peptide metabolism and signaling kinetics

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Exclusion criteria included prematurity, being small for gestational age, neurological or psychiatric disorders, ADHD, movement disorders, syndromic short stature, additional pituitary hormone deficiency, known sleep disorder, known medical therapy for a chronic condition, or less than 6 months of growth hormone treatment