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The challenge: GH production declines progressively with ageapproximately 14% per decade after age 30

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Evidence type: Human studies | Animal

3.5 Regulation of sympathetic activity Cyclic enhancement of sympathetic nerve activity is observed in OSAHS, as indicated by increased muscle sympathetic nerve activity (MSNA) (99), elevated urinary norepinephrine concentrations (100), and reduced heart rate variability (101), which persists during wakefulness (102)