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Gradual weight reduction allows hormonal systems to adapt, while rapid loss triggers more pronounced menstrual disruptions

It is also approved to reduce the risk of major adverse cardiovascular events in adults with type 2 diabetes and established cardiovascular disease (Ozempic), and in adults with established cardiovascular disease and either obesity or overweight (Wegovy)

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Regular monitoring of dietary intake through food logs or mobile applications can help ensure adequacy, particularly during the first three to six months of treatment when appetite suppression is most pronounced

doi: 10.1093/ndt/gfad009