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Lifestyle changes promoting a reduction in caloric intake and an increase in energy expenditure represent the first-line action [4]

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In controlled research settings, this compound is used to investigate

In a one-year randomized trial in older adults, a walking program increased anterior hippocampal volume by about 2 percent, while the same region shrank by about 1.4 percent in the control group, against a normal loss of 1 to 2 percent a year at this age

As expected, the BHBA-induced increase of p-CaMKII was reduced to the basal level by KN-62 (Figure 4A)