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Role of presynaptic muscarinic and GABA(B) receptors in spinal glutamate release and cholinergic analgesia in rats
The latest study by the same group suggests that this effect may result from Mn impairing lysosomal protein degradation (Rokad et al., 2024)
Analysis of serum and urine Glu and PyroGlu and erythrocyte GPX1 activity correlation with inflammation and severity status PyroGlu, Glu, and GPX1 activity levels were associated with severity parameters (APACHE II, SOFA, days of mechanical ventilation, days of stay in ICU, and age) and mortality
however, if only key grading nodes were missing, the study was not excluded but was strictly downgraded during the evidence grading process
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