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Calculation of the actual potential in biological samples from concentration measurements is further complicated by vague estimations of subcellular compartment volumes and artifacts occurring during sample work-up

So, gut permeability problems are inherent in someone with Hashimotos, which leads to poor nutrient extraction and absorption

doi:10.1073/pnas.94.5.1967 19

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The BPC-157 research materials discussed commercially are synthetically produced 15-residue peptides and should not be described simply as naturally extracted human products