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Lopez N, Tormo C, De Blas I, Llinares I, Alom J

The GSSG-dependent oxidation of roGFP2 by fused PfGrx variants is two to three orders of magnitude faster than the oxidation by unfused PfGrx(SSG) variants and more than seven orders of magnitude faster than the uncatalyzed reaction with GSSG (Table 1)

Activation of p53 by Novel MDM2 Antagonist RG7388 Overcomes AML Inherent and Acquired Resistance to Bcl-2 Inhibitor ABT-199 (GDC-0199)

Methionine synthase and methionine synthase reductase ( MTR and MTRR ) MTR is a cobalamin-dependent enzyme that catalyzes the transmethylation of hcy to methionine and MTRR, a NADPH-dependent diflavin enzyme, is required for the reductive activation of MTR (Figure 1)

Regulatory pathways in programmed cell death